Sprinters and fast road riders who picked aero over weight. If you wanted the climbing bike in this era, compare stack/reach against the Émonda instead.
Gen 7 Madone: a pure aero race bike built on Kammtail Virtual Foil tubes with the IsoFlow cutout for rear compliance. It is the fast, heavier half of Trek's race line — Émonda is still the light bike in these years.
CX and gravel racers who already like Santa Cruz. Not a bikepacking mule.
Drop-bar Santa Cruz: CX/gravel race geometry, not a touring bike. It feels like the brand's MTB handling translated to drop bars.
CX racers. If you want gravel capability, look at Checkpoint or Checkmate instead.
A UCI cyclocross race bike with IsoSpeed on some generations. Tight, muddy, and built to be shouldered — not a Checkpoint with CX tires.